Glucagon-like peptide-1 receptor agonists in neurodegenerative diseases: a bibliometric analysis of global research trends and research hotspots from 2006 to 2025.
Naunyn-Schmiedeberg's archives of pharmacology · · Bi Q, Zhang L, Zhang J +6
Research
Latest Peptide Research
The most recent peer-reviewed peptide studies indexed in PubMed, refreshed regularly and tagged by compound. Every entry links to the primary source.
90 recent papers from the last 120 days. Source: PubMed (NCBI E-utilities). Updated July 2, 2026. Peptide Science Daily indexes citations and links to the original record on PubMed; we do not reproduce article abstracts.
Association of Tirzepatide versus Glucagon-Like Peptide-1 Receptor Agonists with Incident Glaucoma in Patients with Type 2 Diabetes: A Retrospective Cohort Study.
Ophthalmology science · · Pan SY, Weng CH, Sheen YJ +4
Weight loss and cardiovascular outcomes with incretin-based therapies after metabolic and bariatric surgery: a nationwide US cohort study.
EClinicalMedicine · · Gillikin A, Lee Y, Varney C +4
Starvation-Type Euglycemic Ketoacidosis After Unsupervised Tirzepatide Use in a Non-Obese, Non-Diabetic Woman.
The American journal of case reports · · Abdelshafey EE, Sewify K, Almutairi A +5
Contractile effects of dulaglutide in the human atrium.
Naunyn-Schmiedeberg's archives of pharmacology · · Neumann J, Jarikova M, Hofmann B +2
Corrigendum to "Oroxylin A suppress LL-37 generated rosacea-like skin inflammation through the modulation of SIRT3-SOD2-NF-κB signaling pathway" [Int. Immunopharmacol. 129 (2024) 111636].
International immunopharmacology · · Feng C, Zhang H, Wang P +9
AMCP Market Insights: Managed care considerations in Barth syndrome.
Journal of managed care & specialty pharmacy · · Flavin B, Vernon HJ, Todd Cade W +5
Humanin Mitigates Aβ-Induced Retinal Pigment Epithelium Injury via AMPK-Beclin1-Dependent Mitophagy.
Aging cell · · Jang HY, Choi S, Kim SJ +5
Glucagon-Like Peptide-1 Agonist vs. Placebo and Pulmonary Decline After Open-Heart Surgery: A Substudy of the GLORIOUS Randomised Clinical Trial.
Acta anaesthesiologica Scandinavica · · Mikkelsen AD, Wiberg S, Schultz HHL +7
Chronic Exposure to 6PPD-Q Induces HPO Axis Dysfunction and Metabolic Disturbances in Female Offspring Mice.
Journal of agricultural and food chemistry · · Jiang Y, Ruan Y, Zeng Z +3
Dulaglutide in the era of tirzepatide and semaglutide: reaffirming its role in contemporary cardiometabolic care.
Diabetology international · · Samajdar SS, Joshi S, Saboo B +2
Hair Loss in Patients on Glucagon-Like Peptide 1 Receptor Agonists: Understanding Risks and Managing Outcomes.
Dermatology and therapy · · Piraccini BM, Vañó-Galván S, Blume-Peytavi U +2
Tirzepatide for Recurrent Weight Gain after Bariatric Procedures: Real-World Evidence of Efficacy and Safety.
Obesity surgery · · Vinciguerra F, Di Stefano C, Guccione F +6
Tirzepatide for weight and behavior management in a patient with Smith-Magenis syndrome.
JCEM case reports · · Liao XC, Huang T, Hong DS +1
Correction to "Aggregation-driven expression of liraglutide precursors using engineered mini-tags in Escherichia coli".
Protein science : a publication of the Protein Society ·
Comparative Effectiveness of CagriSegma, Semaglutide, Cagrilintide and Tirzepatide in the Management of Overweight and Obesity: A Network Meta-Analysis of Randomized Clinical Trials.
Endocrinology, diabetes & metabolism · · Hamarsheh S, Jaber AR, Abu-Khazneh O +4
Effects of dapagliflozin and dulaglutide on blood pressure and coronary flow in liver steatosis patients with type 2 diabetes.
Journal of hypertension · · Ikonomidis I, Michalopoulou E, Pavlidis G +16
GLP-1R R131Q links long-range conformational remodeling to cellular stress phenotypes.
Journal of molecular graphics & modelling · · Kato T, Inomata N, Serizawa K +8
The glucagon-like peptide-1 receptor agonist, Ex4, reduces intromission in sexually experienced male mice.
Psychoneuroendocrinology · · Shevchouk O, Edvardsson CE, Ericson M +2
GLP-1 receptor agonists and surgical care: implications for bariatric Procedures, perioperative Outcomes, and nutritional optimization.
Diabetes research and clinical practice · · Elawa Z, Khalil A, Kardousha A +2
A glucose-responsive dual-nanoparticle-hydrogel-based microneedle patch for co-delivery of insulin and exendin-4.
Biomaterials science · · Zhang T, Liu S, Ma Q +4
Liraglutide and Recurrent Stroke by Baseline Insulin Resistance: A Post Hoc Analysis of the LAMP Trial.
Stroke · · Lu L, Yang B, Wang Y +10
LAT1-mediated delivery of engineered R13A-MOTS-c attenuates radiation-induced lung injury via Nrf2 activation and mitochondrial protection.
Redox biology · · Zhang YL, Huang G, Li SP +6
Novel GLP-1RA-like effects of Bafetinib: a preliminary study integrated in vitro screening and in vivo validation.
Toxicology and applied pharmacology · · Zheng X, Xu Q, Wei Y +4
A comparison of the effects of tirzepatide and dulaglutide on major kidney events in people with type 2 diabetes: pre-specified exploratory analyses of the SURPASS-CVOT trial.
The lancet. Diabetes & endocrinology · · Zoungas S, D'Alessio D, Pavo I +21
Incretin-Based Anti-obesity Medications in Polycystic Ovary Syndrome: The Evidence Map.
Drugs · · Jensterle M, Janez A
Clinical Characteristics of Users of Weight Loss Drugs: Population-Based Case-Control Study.
Diabetes, obesity & metabolism · · Bakken IJ, Ruiz PL, Furu K +6
Elamipretide (SS-31) promotes recovery by preserving mitochondrial bioenergetics and neural remodeling after spinal cord injury.
Neurochemistry international · · Song Z, Ban Z, Zhao H +1
Three-year changes in renal function after switching from injectable GLP-1 receptor agonists to oral semaglutide in Japanese patients with type 2 diabetes: a retrospective cohort study.
Diabetology international · · Takashima S, Terui K, Yamada F +1
Gut-Derived GLP-1 Released by Rare Sugar d-Allulose Cooperates With Insulin to Activate Left-Sided Vagal Afferents and Enhance Insulin Sensitivity.
Diabetes · · Ohbayashi K, Tanida M, Abe C +6
Semaglutide for treatment of intractable diarrhea of different etiologies: a case series of 30 patients.
Scandinavian journal of gastroenterology · · Nielsen GL, Hellström PM, Olesen SS +1
Use of Glucagon-Like Peptide-1 Receptor Agonists and Risk of Parkinson's Disease: Scandinavian Cohort Study.
Diabetes, obesity & metabolism · · Engström A, Svanström H, Hviid A +8
Pharmacokinetic Bioequivalence of Orforglipron Tablets and Capsules in Healthy Participants With Obesity or Overweight.
Diabetes, obesity & metabolism · · Ma X, Li YG, Raha S +3
Cardiometabolic Profiles of Oral and Subcutaneous Glucagon-Like Peptide-1 Receptor Mono-Agonists in Adults With Overweight or Obesity: A Systematic Review and Network Meta-Analysis.
Diabetes, obesity & metabolism · · Lu Y, Chen J, Guo Y +6
Approved weight loss drugs for obesity with a thorough emphasis on GLP-1 agonist medications: A systematic review.
Disease-a-month : DM · · Gunasekaran P, Inban P, Agrawal A +5
Neurokinin receptor antagonists for vasomotor symptoms: from KNDy neurons to clinical translation.
Nature reviews. Endocrinology · · Torres E, Wall EG, Navarro VM
Mitochondrial-derived peptide MOTS-c targets SLC7A11 to preserve spermatogenesis by suppressing ferroptosis.
Free radical biology & medicine · · Liu S, Ru K, Shen YJ +12
Comparative Effectiveness of Liraglutide versus Dulaglutide in Heart Failure With Preserved Ejection Fraction: A Multicenter Propensity Score-Matched Real-World Study.
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · · Khalil I, Hossain MI, Sarker P +6
A new era of doping? Use of peptide and peptide-analog drugs in recreational and professional sport and bodybuilding: a critical review.
The Journal of sports medicine and physical fitness · · Coutinho LFD, DE Oliveira Neves LF, Camilo RP
Humanin as an evolutionarily tuned mitochondrial peptide: Insights from mammalian oxidative stress diversity.
Free radical biology & medicine · · Shahzaib M, Aprile D, Alessio N +4
Corrigendum to "Exendin-4 alleviates Aβ1-40-induced apoptosis and calcium dysregulation in RPE cells through the CHP1/NHE1 complex" [Biochem. Pharmacol. 247 (2026) 117789].
Biochemical pharmacology · · Shu Q, Lin Y, Su W +2
Targeting the NR5A1-KISS1R-EMT axis with a small-molecule inhibitor suppresses lung adenocarcinoma progression and metastasis.
Cellular signalling · · Wang D, Hui K, Yuan C +7
Assessing the risk of diabetic retinopathy progression with GLP-1 receptor agonists: a systematic review and meta-analysis.
BMC ophthalmology · · Yang Q, Hassan W, Ahmed H +1
High-yield, standardised automated radiosynthesis process for routine clinical insulinoma PET with [⁶⁸Ga]Ga-NODAGA-exendin-4.
EJNMMI radiopharmacy and chemistry · · Duray E, Sacrez M, Hawotte M +4
The kisspeptin analog C6 elicits greater tachyphylaxis and transcriptional activation than kisspeptin-10 and -54.
Molecular and cellular endocrinology · · Robert V, Lomet D, Dardente H +2
Antimicrobial peptoids pass rapidly through bacterial membranes and flocculate ribosomes and DNA: A single-cell fluorescence study.
Proceedings of the National Academy of Sciences of the United States of America · · Zhu Y, Nielsen JE, Molchanova N +11
Stress as a Neuroendocrine Modulator of the Reproductive Axis: Roles of Glucocorticoids, Kisspeptin and Serotonergic Signalling in Animal Models.
Neuroendocrinology · · Chisupa CO, Manchishi SM
Effect of Retatrutide, a Novel Triple Receptor Agonist, on Blood Pressure and Lipid Levels: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · · Simental-Mendía LE, Barragán-Zúñiga LJ, Reyes-Avitia V
Ease of Use, Ease of Learning, and Convenience of the CagriSema Dual-Chamber Pen: Results From a Usability Study in Adults With Overweight, Obesity, or Type 2 Diabetes.
Journal of diabetes science and technology · · Gulisano W, Ter-Borch G, Brown P +6
GLP-1 receptor agonists in pediatric obesity and diabetes: a systematic review of efficacy, metabolic effects, and safety.
Diabetes research and clinical practice · · Soliman AT, Alyafei F, Khalil A +4
Kisspeptin-2 stimulates testicular function in adult pejerrey (Odontesthes bonariensis): Does it act directly on the testes?
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology · · Pérez MR, Mechaly AS, López GC +3
Kisspeptin-10/basal LH ratio improves differentiation of central precocious puberty and premature thelarche.
Clinica chimica acta; international journal of clinical chemistry · · Banerjee AA, Bhanarkar SR, Kashikar S +14
Efficacy and safety of orforglipron in obesity with type 2 diabetes mellitus: a GRADE-assessed meta-analysis of randomized controlled trials.
Diabetology & metabolic syndrome · · Emara A, Emara M, Mansour A +5
Reduced SuM Activation Accompanies Impaired Social Novelty Recognition in Mouse Models of Neurodevelopmental Disorders.
eNeuro · · Maejima R, Ito Y, Motoyama J
Clinical development in primary mitochondrial diseases at a translational inflection point: Lessons, mechanisms, and emerging therapeutic strategies.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · · Wang LT, Jhuang HY
Topology-Controlled PEGylation Enhances Renal Accumulation of Therapeutic Peptide for Treating Ischemia-Reperfusion Injury.
Nano letters · · Wen Y, Zhao Z, Zheng X +6
Circulating mitochondrial-derived microproteins at rest and in response to an acute bout of endurance exercise in individuals with cerebral palsy.
Experimental physiology · · Horwath O, Corell L, Wan J +9
Host antimicrobial peptide LL-37 inhibits CovS kinase activity and antagonizes CovR-Mediated activation in group A Streptococcus.
Biochemical and biophysical research communications · · Wu L, Wang L, Chen S +5
Goldilocks-Inspired Design of Mid-Size Macrocycles for Selective Targeting of Human Melanocortin Receptors.
Journal of medicinal chemistry · · Merlino F, Jia L, Boccino I +5
The evolution and functional significance of neuropeptide cocktails: insights from SALMFamides in asteroid echinoderms.
Open biology · · Escudero Castelán N, Elphick MR
Hepatic Safety of Orforglipron in Adults With Obesity or Overweight and/or Type 2 Diabetes: A Pooled Analysis of the Orforglipron Phase 3 Clinical Trials.
Diabetes, obesity & metabolism · · Wharton S, Stefanski A, Chen J +3
Combined nonoxynol-9 and antimicrobial peptide LL-37 for barrier contraception.
Reproduction & fertility · · Xu M, Chan CPS, Cong L +3
Weekly Journal Scan: Tirzepatide did not SURPASS the cardiovascular benefits of dulaglutide in type 2 diabetes.
European heart journal · · Liuzzo G, Patrono C
Therapeutic Effects of Glucagon-like Peptide-1 Receptor Agonists in Non-Alcoholic Fatty Liver Disease: A Systematic Review.
International journal of molecular sciences · · Mahoon D, Kellany F, Khan I +2
Dual Glucagon and GLP-1 Receptor Agonist Survodutide Improves Biomarkers of Beta-Cell Function and Insulin Sensitivity in People With Type 2 Diabetes or Living With Overweight/Obesity.
Diabetes, obesity & metabolism · · Ekinci EI, Maldonado SG, Unseld A +3
Immunomodulatory and Gut Microbiota-Regulating Effects of Lactobacillus helveticus LH76 in Healthy Adults: Preclinical Safety Assessment and a Randomized, Double-Blind, Placebo-Controlled Trial.
Probiotics and antimicrobial proteins · · Song S, Ding L, Yang T +6
Rapid and harmonized analytical workflow for the determination of peptidic and non-peptidic doping agents in dried and liquid blood matrices.
The Analyst · · Mazzarino M, Colpaert T, Deventer K +1
Mitochondrial-derived peptide MOTS-c activates metabolic signaling but blunts reparative function in human mesenchymal stromal cells.
Inflammation and regeneration · · Xing L, Lu B, Zhu X +5
Orforglipron for the treatment of moderate-to-severe obstructive sleep apnea in adults with obesity or overweight: Study design and baseline characteristics of ATTAIN-OSA, a phase 3 trial.
Contemporary clinical trials communications · · Malhotra A, Gottlieb DJ, Kundel V +4
Mitochondrial peptide MOTS-c suppresses systemic and cardiac inflammasome activation in a diabetic rat model.
Experimental physiology · · Mills AR, de Souza A, Pham T +1
Novel Anti-Microbial Peptides Design and Screening Against the KatG Using Molecular Docking and MD Simulation.
Probiotics and antimicrobial proteins · · Mehta K, Mujawar S, Kumar G +1
Micronutrient risk with GLP-1 receptor and dual incretin agonists in obesity: Mechanistic pathways, clinical signals, and a monitoring framework.
Obesity pillars · · Simancas-Racines D, Campuzano-Donoso M, Rossetti G +7
Obstetrical and medical outcomes following GLP-1 receptor agonist exposure in pregnancy: a case series.
Case reports in women's health · · Wong K, Al-Amri H, Werlang A
The effect of growth hormone-releasing hormone on cognition and brain connectivity in adults with cognition ranging from normal to mild cognitive impairment.
eNeurologicalSci · · Stewart CE, French KP, Wright TJ +11
β-Amyloid (Aβ) and Human Cathelicidin LL-37: Two Sides of the Same Coin?
International journal of molecular sciences · · Asti AL
Bifidobacterium lactis XLTG11 Reduces Eczema and Infections in Infants: A Randomized Trial.
QJM : monthly journal of the Association of Physicians · · Yuan Y, Yin X, Liu J +9
Pre-synchronization with GnRH or hCG enhances fertility outcomes of heat synch protocol in Holstein dairy cows across parities: A pilot study.
Veterinary and animal science · · Navidifar P, Kaveh A, Hosseini SE +5
Neurohormonal-Immune Dysregulation in Rosacea: Emerging Perspectives from the Skin-Gut-Brain Axis.
Drug design, development and therapy · · Shi L, Li S, Yao X +9
Exposure to the antimicrobial peptides LL-37 and ATRA-1 induces a lipidome response in Staphylococcus aureus that alters membrane biophysical properties.
Biochimica et biophysica acta. Biomembranes · · Fuertes-Chaves C, Gonzalez JE, Suesca E +5
Benefits and Harms of Pharmacologic Treatments in Adults With Overweight or Obesity: A Living Systematic Review and Network Meta-analysis for the American College of Physicians.
Annals of internal medicine · · Damen JAA, Idema DL, Vernooij RWM +9
Hierarchical regulation and mechanism of "open-hollow-fibrous network" structures: Osteogenic-angiogenic coupling responses of poly(γ-benzyl-L-glutamate) microspheres.
Biomaterials advances · · Su J, Zhang Y, Cao Y +4
Thymosin Alpha-1 Restores Chemotherapy-Induced Antitumor Immunity by Chaperoning a MicroRNA Ligand of TLR7 in Dendritic Cells.
Cancer research · · Wei Y, Chen J, Zhang Y +14
Salivary antimicrobial peptides histatin-5, beta defensins, human neutrophilic peptides, LL-37, and calprotectin in severe dental caries, with a focus on early childhood caries: a systematic review and meta-analysis.
Odontology · · Muruganandhan J, Veeraraghavan VP, Sujatha G +2
Targeting Mitochondrial Dysfunction With Elamipretide (SS-31) Improves Skeletal Muscle Performance in a HFpEF Rat Model.
Circulation. Heart failure · · Vahle B, Weidner S, Tomalka A +11
In vitro metabolic profiling of weight-loss-inducing amylin receptor agonists in the context of preventive doping research.
Journal of pharmaceutical and biomedical analysis · · Alhalabi H, Borschel L, Le Foll C +3
Efficacy and safety of retatrutide, a GIP, GLP-1, and glucagon receptor agonist, in people with type 2 diabetes and inadequate glycaemic control with diet and exercise (TRANSCEND-T2D-1): a double-blind, randomised, phase 3 trial.
Lancet (London, England) · · Bajaj HS, Welch M, Shah P +7
Semaglutide and major adverse cardiovascular events in patients with and without DM: A systematic review and meta-analysis.
Biomedical reports · · Li Y, Lv C, Cao L +2
GLP-1 Agonists in Adolescent Obesity: A Narrative Review of Single, Dual, and Triple Agonists.
Diabetes, metabolic syndrome and obesity : targets and therapy · · Abid M, Sheikh KS, Ahmad MS +1
A Hydrophobic Tag-Assisted Liquid-Phase Strategy for the Synthesis of Retatrutide.
Organic letters · · Mao CY, Pang ZJ, Qiao GY +1
Change in circulating irisin level and its association with lipid metabolism after exenatide treatment in patients with type 2 diabetes mellitus.
Journal of clinical & translational endocrinology · · Gao Y, Hong X, Yang K +5