Medical treatments for obesity: what does the future have in store?
The Journal of clinical endocrinology and metabolism · · Bassatne A, Rizo I
Research
Latest Peptide Research
The most recent peer-reviewed peptide studies indexed in PubMed, refreshed regularly and tagged by compound. Every entry links to the primary source.
90 recent papers from the last 120 days. Source: PubMed (NCBI E-utilities). Updated October 16, 2026. Peptide Science Daily indexes citations and links to the original record on PubMed; we do not reproduce article abstracts.
68Ga-DOTA-exendin-4 PET/CT for insulinoma localization in patients with negative or inconclusive conventional imaging.
The Journal of clinical endocrinology and metabolism · · Fricke JG, Laubner K, Schildmeijer M +7
Retatrutide and lipid and metabolite profiles in participants with obesity with or without type 2 diabetes.
The Journal of clinical endocrinology and metabolism · · Pearson MJ, Willency JA, Lin Y +8
Brain-Specific Quantification of Somatostatin Receptor Expression: SUV(max) and SUVR(sss) as Quantitative Correlates of the Krenning Score in Meningioma.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine · · Marulanda-Corzo V, Farid M, Hill T +14
Familial Sex Trafficking of Minors: we are A Study of Scope, Characteristics, and Systemic Challenges Across the U.S. Justice Process.
Violence and victims · · Wyatt SL, Allert JL
Octreotide attenuates pancreatic fibrosis through modulation of the HMGB1-Wnt/β-catenin axis in experimental chronic pancreatitis.
Molecular and cellular biochemistry · · Lu W, Huang S, Wang J +2
Retatrutide treatment in streptozotocin-induced diabetic rats: renal inflammatory cytokines, HIF‑1α expression, and histopathological injury profile.
Journal of molecular histology · · Keskin U, Altın E, Özatik FY +4
New Horizons in Pharmacotherapy for Cushing's Disease and Acromegaly.
Endocrine-related cancer · · Fleseriu M, Melmed S, Labadzhyan A
Acquired hypothalamic obesity as α-MSH deficiency syndrome: a paradigm shift with therapeutic impact.
Molecular and cellular pediatrics · · Wabitsch M, Ulrich K, Denzer C
New and emerging pharmacological treatment options for acromegaly: a 2026 update.
Expert opinion on pharmacotherapy · · Wildemberg LE, Marques NV, Kasuki L +1
Outcomes in patients with diabetes, atherosclerotic cardiovascular disease, and heart failure treated with tirzepatide or dulaglutide: SURPASS-CVOT analysis.
European journal of preventive cardiology · · Nicholls SJ, Pavo I, Bhatt DL +19
Setmelanotide for the Treatment of Acquired Hypothalamic Obesity. Reply.
The New England journal of medicine · · Roth CL, Miller JL
Setmelanotide for the Treatment of Acquired Hypothalamic Obesity.
The New England journal of medicine · · Ou Q, Tang J
Setmelanotide for the Treatment of Acquired Hypothalamic Obesity.
The New England journal of medicine · · Zhang J, Zhan X, Li T
MOTS-c in sepsis-induced cardiomyopathy: Mechanisms and translational potential.
European journal of pharmacology · · Zhao Z, Chen W, Zheng X +5
Activation of the dopamine D2 receptor enhances colonic motility via disinhibition of somatostatinergic signalling in rodents.
European journal of pharmacology · · Zhang CF, Zhang XL, Zhang JH +3
WITHDRAWN: Corrigendum to "Oroxylin A suppress LL-37 generated rosacea-like skin inflammation through the modulation of SIRT3-SOD2-NF-κB signaling pathway" [Int. Immunopharmacol. 129 (2024) 111636].
International immunopharmacology · · Feng C, Zhang H, Wang P +9
Effect of Romosozumab on Localized Periosteal Thickening: A Precursor to Atypical Femoral Fractures.
The Tohoku journal of experimental medicine · · Sato H, Kondo N, Hasegawa E +7
Detection of CJC-1295 in Equine Plasma by ELISA.
Drug testing and analysis · · Timms M, Cawley A, Steel R
The GLP-1R/GCGR Dual Agonist Mazdutide Attenuates Liver Steatosis and Decreases Circulating Cholesterol Levels in Mice With Metabolic Dysfunction-Associated Steatotic Liver Disease.
Diabetes, obesity & metabolism · · Yu L, Wang G, Zhang J +3
Device-Free Auricular Acupressure for Rosacea: A Randomized Clinical Trial.
JAMA dermatology · · Xu B, Chu J, Wang Y +13
Reassessing the Neoplasm Signal with Fezolinetant: Regulatory Inference, Mechanistic Plausibility, and the Case for Proactive Pharmacovigilance.
Drug safety · · Clack G, Renwick J
Efficacy of low-dose pioglitazone in combination with exenatide on glucose control in patients with T2DM.
BMJ open diabetes research & care · · Abdul-Ghani MA, Abu-Farha M, Puckett C +11
Plasma amylin levels in migraine and after erenumab treatment: A REFORM study.
Headache · · Domínguez-Moreno R, Alexander TI, Karlsson WK +6
The pharmacotherapy for pediatric obesity: insights and challenges from adult weight-loss medications.
Journal of diabetes and metabolic disorders · · Chen Z, Zhou Y, Li G +5
Kisspeptin-10 alleviates OGD/R-induced H9c2 cardiomyocyte injury by triggering autophagy via regulating the YY1/TFEB axis.
Cytotechnology · · Li Q, Liu H, He Y +4
Use of Desmopressin in Spontaneous Nontraumatic Intracerebral Hemorrhage Among Patients Taking Antiplatelet Therapy: Systematic Review and Bayesian Meta-analysis.
Neurocritical care · · Łajczak P, de Oliveira RR, Łajczak A +2
Does Survodutide Provide Renoprotection Beyond Its Metabolic and Haemodynamic Effects in Diabetic Kidney Disease?
Diabetes, obesity & metabolism · · He J
Humanin attenuates neuronal cellular senescence and preserves neurotransmitter release in differentiated PC12 cells.
Neuroscience · · Tanahashi M, Kozuka A, Sasakawa N +1
In brief: A cardiovascular indication for tirzepatide (Mounjaro).
The Medical letter on drugs and therapeutics ·
Mitochondrial-derived peptides in female reproduction: Emerging regulators of oocyte competence and novel therapeutic opportunities for infertility.
Tissue & cell · · Rostami Z, Galeshi M, Mosapour A
Acute Hemorrhagic Manifestations in a Pregnant Patient With Type 1 von Willebrand Disease: Challenges in Management of Bleeding Disorders During Gestation.
Clinical case reports · · Rojas-Oviedo JL, Walteros MFL, Pérez DLM +3
Efficacy of Tenapanor in Patients With or Without Prior Use of IBS-C Prescription Medications: A Post-hoc Analysis of Phase 3 Clinical Trials.
Digestive diseases and sciences · · Shah E, Lacy B, Williams L +4
Managing Rebound Bone Loss After Denosumab Discontinuation: Mechanisms, Risk Stratification, and Sequential Therapy.
Drug design, development and therapy · · Ahmad, Liao Y, Yu M +6
Retatrutide in adults with obesity and type 2 diabetes: what have we learned from TRIUMPH-2?
Lancet (London, England) · · Holst JJ
Retatrutide in adults with obesity and type 2 diabetes (TRIUMPH-2): a double-blind, parallel-group, randomised, placebo-controlled, phase 3 trial.
Lancet (London, England) · · Bellido V, le Roux CW, Ekinci EI +8
Oral Obesity Medicines in the Era of Cardiovascular-Kidney-Metabolic Syndrome (CKM): Beyond Weight Loss Toward Disease Modification.
Drug design, development and therapy · · Alhazmi A, Le Roux CW
The Effect of Exanatide on Recovery of the Facial Nerve Crush Injury in the Rat.
The journal of international advanced otology · · Yılmaz B, Şahin Yılmaz AA, İla K +3
SLC32A1 regulates puberty onset in female mice by modulating GnRH neuron function through Kisspeptin and GABA-GABA(B) receptor signaling.
Theriogenology · · Pan Z, Zhang W, Han K +6
Wendan decoction-derived TMF alleviates endolymphatic hydrops by modulating the DUSP3/p38 MAPK/AQP2 axis.
Journal of ethnopharmacology · · Xia J, Huang J, Hou X +2
Analysis of a case of immune-related pancreatitis induced by anti-PD-1 antibody therapy for gastric cancer: A case report.
Medicine · · Zhang F, Xiao W
Unapproved GLP-1 Drugs Retatrutide and Zenagamtide Sold Online Are No Bargain.
JAMA · · Rubin R
Case Report: Atypical femoral fractures in adult-onset hypophosphatasia treated with low-dose asfotase alfa and adjunctive teriparatide therapy.
Frontiers in endocrinology · · Chung YS, Kim KK, S GB +1
A Case of Misdiagnosed Pediatric Congenital Nephrogenic Diabetes Insipidus due to AQP2 Variants.
Case reports in pediatrics · · Chirico V, Cassaro F, Sbilordo S +10
Human genetic evidence challenges NCOA1 as a monogenic obesity gene.
Cell reports. Medicine · · Delplanque J, Leloire A, Le Collen L +14
Copeptin and urine concentrating capacity predict kidney function decline in lithium-treated patients.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · · Zittema D, van der Aa M, Doornebal J +5
Iatrogenic hyponatremia during the diagnostic workup of hypercortisolism: when the search for a diagnosis becomes a clinical threat.
Endokrynologia Polska · · Wieczorkiewicz T, Witek K, Dzialach L +2
LL-37-MRGPRX2-Mast Cell Signaling in Rosacea: Current Evidence and Directions for Human Studies.
Clinical, cosmetic and investigational dermatology · · Yin H, Lu Y
Lysine-Proline-Valine attenuates oxidized low-density lipoprotein-induced foam cell formation and inflammatory responses in RAW264.7 macrophages.
Tissue & cell · · Bai JS, Kim RW, Li Y +3
Emerging risks of health optimisation: refractory nausea associated with peptide injections reported to contain retatrutide.
BMJ case reports · · Buzzi RM, Huber LC
Micro/nanoparticle hybrid hydrogel platform with mild photothermal stimulation on abaloparatide in situ release for cranial bone regeneration.
Journal of materials chemistry. B · · Wu Y, Lu W, Salas-Hernandez JL +5
Rethinking Platelet Dysfunction in Traumatic Brain Injury: From Platelet Count to Hemostatic Phenotype.
Neurocritical care · · Quintana Diaz M, Godoy DA
Design and baseline characteristics of the CagriSema cardiovascular outcomes trial (REDEFINE 3).
American heart journal · · Cavender MA, Jastreboff AM, Cheng AYY +9
Correction: Co-delivery of doxorubicin and siRNA using octreotide-conjugated gold nanorods for targeted neuroendocrine cancer therapy.
Nanoscale · · Xiao Y, Jaskula-Sztul R, Javadi A +6
Treatment of male osteoporosis: a narrative review and position statement by the ECTS Clinical Action Group.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · · Sølling AS, Paccou J, Anastasilakis AD +8
Cardiovascular outcomes with tirzepatide versus semaglutide in type 2 diabetes.
Journal of diabetes and metabolic disorders · · Al-Nusair M, Khurana S, Eysha M +2
Effectiveness and Safety of Pharmacological Therapy for Osteoporosis in Frail Elderly Individuals: Systematic Review and Meta-Analysis.
Health science reports · · Freire AJLR, Gazoni FM, Carvalho EH +1
Bidirectional pharmacology of GIP receptor targeting in obesity: Historical foundations, mechanistic divergence, and translational boundaries.
Peptides · · Liu C, Wang Y, Liu J +5
Lymphocele After Radical Prostatectomy: A Systematic Review of Risk Factors and Quantitative Synthesis Preventive Strategies.
World journal of urology · · Çavdar ÖF, Akgül B, Güldibi F +8
Prognostic Value of Intraoperative Desmopressin Test for Long-Term Remission in Cushing's Disease: A Prospective Cohort Study.
Neurosurgery · · Zhang H, Wang B, Ren J +5
Is there a difference in ovarian hyperstimulation syndrome rates in freeze-all treatment cycles in high-risk patients treated with different GnRH agonist triggers?
Human fertility (Cambridge, England) · · Shah R, Barcroft J, Al-Lamee H +10
Factors Affecting the Clinical Response to Desmopressin Treatment for Primary Monosymptomatic Nocturnal Enuresis in Children.
Neurourology and urodynamics · · Selvi I, Canbaz FA
Arginine vasopressin deficiency revealing a disseminated human chorionic gonadotropin-secreting germinoma.
JCEM case reports · · Vargas Santiago R, Kaur S, Tsomos E
Off-label palopegteriparatide for severe pediatric postsurgical hypocalcemia.
European journal of endocrinology · · Pérez Reyes P, Rebollo Román Á, Alhambra Expósito MR +5
The role of biorelevant media components on the diffusion and enzymatic stability of oral cyclic peptide analogs.
International journal of pharmaceutics · · Al-Tamimi Z, Southard B, Melendrez Cuadros ML +2
Bone response to intermittent parathyroid hormone (PTH) is both genetic and sex specific in mice.
Bone · · Adams DJ, Godfrey DA, Ridoux SE +4
Nisotirostide (LY3457263), a novel NPY2 receptor agonist for type 2 diabetes and obesity: From discovery to clinical proof of concept.
Molecular metabolism · · Briere DA, Leohr JK, Linnebjerg H +10
Denosumab-efficacy, safety, persistence and sequential strategies-a systematic review.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · · Laursen NA, Sølling AS, Harsløf T +1
Differential efficacy of initial versus sequential combination of denosumab and teriparatide in osteoporosis at high fracture risk.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · · Li XP, Chen R, Cheng C +3
Survodutide for the treatment of obesity: Mechanistic rationale, clinical evidence, and remaining uncertainties.
Contemporary clinical trials · · Sergi CM
Comparison of the effects of atypical antipsychotics on decreased libido in zebrafish and their mechanisms.
Behavioural brain research · · Shinokawa K, Hattori S, Miyauchi M +6
Effects of retatrutide on learning and memory in streptozotocin-induced male diabetic rats.
Behavioural brain research · · Keskin U, Altın E, Kara MK +6
Anesthesia Clinical Practice Guidelines for Ehlers-Danlos Syndrome: A Modified Delphi Survey.
AANA journal · · Amaral D, Patrick K, Redeker G +3
Conservative Treatment with Adjunctive Use of Teriparatide for Periprosthetic Humeral Fractures after Reverse Total Shoulder Arthroplasty: A Report of 6 Cases.
Clinics in orthopedic surgery · · Sohn HJ, Park BS, Hwang J +3
Self-Reported Adverse Effects Among Social Media Users Taking Nonapproved Retatrutide.
JAMA network open · · Sehgal NKR, Tronieri JS, Rader B +2
Coexisting focal nodular hyperplasia and diffuse hepatic metastases from an ileal neuroendocrine tumor: a case report and literature review.
International journal of surgery case reports · · Ghannei O, Sboui H, Trimech MB +1
Early neuroendocrine signatures of polyendocrine metabolic ovarian syndrome risk: Pubertal programming, social brain signals, and novel therapeutic targets.
Journal of neuroendocrinology · · Oğuz SH, Yildiz BO
Late recovery from chronic arginine vasopressin deficiency: a multicenter retrospective case-control study.
Journal of the Endocrine Society · · Sailer CO, Galbiati F, Aulinas A +15
Functional interactions between anteroventral periventricular kisspeptin neurons and gonadotropin-releasing hormone neurons in female mice.
Journal of neuroendocrinology · · Starrett JR, Chen X, Krasner D +2
Elamipretide Rejuvenates Oocyte Quality and Restores Female Fertility During Reproductive Aging.
Aging cell · · Zhang HL, Wang Y, Wang C +10
Future directions of osteoanabolic therapies in osteoporosis: Integrating current anabolic agents and emerging senescence-targeted strategies.
Best practice & research. Clinical rheumatology · · Brooks HW, Cusick NC, Wu S +1
Tirzepatide safety in EudraVigilance: descriptive and disproportionality analysis of preferred terms related to suboptimal treatment outcomes and drug-use-related issues.
BMJ open · · Popa Ilie IR, Ghibu S, Butuca A +6
Nephroprotective Effects of the Dual GCGR/GLP-1R Agonist Survodutide in Hypertension-Accelerated Diabetic Kidney Disease.
Diabetes, obesity & metabolism · · Hamilton A, Thisted L, Ougaard M +9
Induced vs Spontaneous Ovulation: Integrating KNDy Circuitry, Sensory Cues, and Ecological Context.
Biology of reproduction · · Xie AA, Hsueh AJ, Xie AA +1
Measuring Hunger Severity in Rare MC4R Pathway Diseases: Development and Psychometric Evaluation of the Most Hunger Item.
Advances in therapy · · Clément K, Roth CL, Kühnen P +7
Effect of Exogenous Danio rerio kiss1 Peptide on Cortisol Levels in Early Embryos and Juvenile Forms of Teleost Fish.
Bulletin of experimental biology and medicine · · Kostina MI, Nuzhnova AA, Blazhenko AA +2
Modern pharmacological management of Osteoporosis: from monotherapy to sequential and combination approaches in postmenopausal women.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · · Rella V, Rotondo C, Barile R +3
Survodutide Once Weekly in Adults with Obesity and Type 2 Diabetes.
The New England journal of medicine · · Wharton S, le Roux CW, Startseva E +28
Weight gain, adipose tissue remodeling and cardiometabolic disease in people with HIV.
Current opinion in HIV and AIDS · · Gorwood J, Capeau J, Béréziat V +1
Divergent effects of hyperandrogenemia on the female reproductive neuroendocrine axis under different physiological conditions.
Journal of neuroendocrinology · · Rose L, Kauffman AS