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Clinical Trials · NCT04191096

Efficacy and Safety of Pembrolizumab (MK-3475) Plus Enzalutamide Plus Androgen Deprivation Therapy (ADT) Versus Placebo Plus Enzalutamide Plus ADT in Participants With Metastatic Hormone-Sensitive Prostate Cancer (mHSPC) (MK-3475-991/KEYNOTE-991)

CompletedPhase 3Gonadorelin (Approved)
Phase
Phase 3
Recruitment status
Completed
Sponsor
Merck Sharp & Dohme LLC
Enrollment
1,251
Start date
Feb 2020
Locations
234 sites, 29 countries
Primary endpoint
Radiographic Progression-free Survival (rPFS) Per Prostate Cancer Working Group (PCWG)-Modified Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST 1.1) as Assessed by Blinded Independent Central Review (BICR)
View Gonadorelin compound reference