Safety

Tirzepatide

Adverse-event report summary for Tirzepatide, drawn from the FDA Adverse Event Reporting System (FAERS).

Total reports
3,153
Reports flagged serious
1,859

“Serious” is FAERS’s own report-level flag (e.g. death, hospitalization, or another outcome the reporter marked as serious) and does not indicate a verified or compound-caused outcome.

Most frequently reported reactions

  1. Product Tampering408 reports
  2. Nausea385 reports
  3. Vomiting342 reports
  4. Diarrhoea268 reports
  5. Fatigue157 reports
  6. Constipation143 reports
  7. Off Label Use143 reports
  8. Drug Interaction142 reports
  9. Drug Ineffective110 reports
  10. Headache106 reports
  11. Dizziness105 reports
  12. Decreased Appetite103 reports
  13. Acute Kidney Injury101 reports
  14. Weight Decreased97 reports
  15. Abdominal Pain94 reports

Counts reflect the most-reported reaction terms (MedDRA preferred terms) associated with reports naming this compound. A single report can list multiple reactions, so reaction counts need not sum to the total number of reports.